Looking for new restaurants opening in Mayfair in 2026? Café Twenty Two is set to open on North Audley Street this September, bringing classic French cooking, Parisian-inspired interiors and cocktails to the heart of central London.
Here are five things to know about Café Twenty Two Mayfair before it opens.
1. Café Twenty Two is opening in Mayfair in September 2026
The Twenty Two will return with a new dining concept, Café Twenty Two, opening in September 2026.
The new restaurant will be located at:
43 North Audley Street, Mayfair, London
An exact opening date has not yet been announced, so this is one to keep on the radar for anyone following new London restaurant openings this autumn.
2. Expect classic French food
Café Twenty Two is being positioned as a relaxed French-inspired restaurant built around simple, classic French cooking.
Rather than an overly formal fine-dining experience, the aim appears to be an energetic neighbourhood café and restaurant that combines good food with the atmosphere of a Mayfair destination.
More details about the full Café Twenty Two menu are expected closer to opening.
3. Guillaume Glipa is behind the new concept
The restaurant is being led by Guillaume Glipa, a well-known figure in London hospitality.
His previous experience includes Chiltern Firehouse, Louie London and Annabel’s, giving Café Twenty Two some serious Mayfair credentials before it has even opened.
His involvement suggests the restaurant will focus as much on atmosphere and hospitality as it does on the food.
4. The interiors mix Mayfair and Paris
Café Twenty Two has also been given a new look.
The interiors are designed to feel warmer and more informal, blending classic Mayfair elegance with Parisian café style.
The idea is to create somewhere suitable for a meal and drinks without losing the sense of occasion associated with dining in Mayfair.
5. There will even be a cocktail trolley
Drinks will play an important part in the new Café Twenty Two experience, with a dedicated drinks menu planned alongside the French food.
One of the more unusual features will be a cocktail trolley, bringing drinks directly to the table and adding a little old-school theatre to the experience.
Further details on menus, prices, reservations and the precise September opening date are still to be announced.
For anyone searching for new restaurants in Mayfair, French restaurants in London, North Audley Street restaurants or London restaurant openings in September 2026, Café Twenty Two looks set to be one of the autumn openings to watch.
Opening: September 2026
Address: 43 North Audley Street, Mayfair, London
Food: Classic French cooking
What to expect: Café-style dining, cocktails and Parisian-inspired interiors
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